Study: The coralbush plant shows potent anti-influenza activity

The coralbush (Jatropha multifida Linn.), a medicinal plant from Myanmar, has been reported to contain antimicrobial, antimalarial, and anti-tumor activities. In the study published in the journal BMC Complementary and Alternative Medicine, the anti-influenza activity of coralbush was evaluated.

  • The coralbush has been used in traditional medicine for treating various diseases.
  • Researchers at the Tokushima Bunri University, University of Toyama, and the University of Yangon prepared four extracts from the stems of the coralbush: water, ethyl acetate, n-hexane, and chloroform extracts.
  • Then, they evaluated the survival of Madin-Darby canine kidney (MDCK) cells, a general model for epithelial cells, infected with the influenza A (H1N1) virus.
  • They also assessed the inhibitory effects of the four crude extracts on influenza A viral infection and growth in MDCK cells.
  • The water stem extract from the coralbush significantly enhanced the survival of MDCK cells infected with influenza A H1N1 virus and inhibited influenza A viral infection.
  • The ethyl acetate and chloroform extracts showed similar, but weaker, effects.
  • The chloroform coralbush stem extract exhibited the strongest inhibition of influenza A viral growth in MDCK cells.
  • The ethyl acetate and n-hexane extracts showed weaker inhibition of influenza A viral growth in MDCK cells.

In conclusion, the findings of the study suggested that the stems of the coralbush posses anti-influenza properties, thus it could be used as an herbal medicine for treating influenza.

Read the full text of the study at this link.

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Journal Reference:

Shoji M, Woo SY, Masuda A, Win NN, Ngwe H, Takahashi E, Kido H, Morita H, Ito T, Kuzuhara T. ANTI-INFLUENZA VIRUS ACTIVITY OF EXTRACTS FROM THE STEMS OF JATROPHA MULTIFIDA LINN. COLLECTED IN MYANMAR. BMC Complementary and Alternative Medicine. 7 February 2017; 17(96). DOI: 10.1186/s12906-017-1612-8

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